Dissecting the host transcriptome and microbiota responses to viral hemorrhagic septicemia virus (VHSV) in the turbot (Scophthalmus maximus) intestine: insights from moribund and asymptomatic phenotypes.

Abstract excerpt

Viral infections profoundly influence host physiology, not only by triggering complex immune responses but also by reshaping the associated microbiota. Conversely, the microbiota can modulate antiviral defenses and disease outcomes through its interactions with the host immune system. This dynamic triad -virus, microbiota, and host immunity-has emerged as a central determinant of infection severity and recovery....

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