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Article

Prognostic value of miR-423-5p in intracranial aneurysm and its mechanism in regulating human brain vascular smooth muscle cell function via SMAD3.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Jun 2026

Liu Weilong, Jia Dandan, Liu Zhenbo

Abstract excerpt

BACKGROUND: Intracranial aneurysm (IA) is a life-threatening cerebrovascular disorder. MicroRNAs exert crucial regulatory functions in IA. However, the role and mechanism of miR-423-5p in IA remain unclear. AIM: To clarify the association between miR-423-5p and the prognosis of IA, and to explore its regulatory effect and mechanism on human brain vascular smooth muscle cells (HBVSMCs). METHODS: 122 IA patients...

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Identifiers

PMID: 42002242
DOI: 10.1016/j.jstrokecerebrovasdis.2026.108638

Genes

SMAD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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