Article
Reconsidering Obesity in India Through a Gut-Metabolic Lens: Mechanistic Insights and the Emerging Role of Synbiotics in Individuals with the Thin-Fat Phenotype.
Advances in therapy - 1 Jul 2026
Ganguly Nirmal Kumar, Kalra Sanjay, Kapoor Nitin, Rao Pariksha, Bakshi Manorama
Abstract excerpt
India's escalating burden of obesity and metabolic disease is characterized by a distinctive "thin-fat" phenotype, in which individuals with normal or near-normal body mass index exhibit disproportionate visceral adiposity, reduced skeletal muscle mass, and heightened susceptibility to insulin resistance. Conventional obesity models centered primarily on caloric imbalance fail to adequately explain this pattern,...
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