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Article

Liver transplantation in severe homozygous familial hypercholesterolaemia: a scoping review.

Atherosclerosis - 1 May 2026

Pang Jing, Gidding Samuel S, Kelty Erin, Raal Frederick J, Cuchel Marina, Hudgins Lisa C, Blom Dirk J, Sorial Elizabeth, Russell Danielle J, Ramachandra Deepti, Ademi Zanfina, Watts Gerald F

Abstract excerpt

BACKGROUND AND AIMS: Liver transplantation is the only known potentially curative treatment for homozygous familial hypercholesterolaemia (HoFH). While this procedure often normalises low-density lipoprotein cholesterol (LDL-C) levels and can reverse coronary atherosclerosis and regress xanthomata, its long-term risks and benefits remain elusive. The purpose of this review was to examine the extant literature on...

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Share to Cholesterol, LDL
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41990429
DOI: 10.1016/j.atherosclerosis.2026.120730

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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