Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Association of Toll-like receptor 5 gene polymorphism with the clinical efficacy of ustekinumab in patients with Crohn's disease].

Zhonghua yi xue za zhi - 21 Apr 2026

Lu J H, Shao X X, Lin D P, Xu Y, Ma G L, Jiang Y

Abstract excerpt

Objectives: To investigate the association of Toll-like receptor 5 (TLR5) gene polymorphisms with the clinical efficacy of ustekinumab (UST) in the treatment of Crohn's disease (CD) patients. Methods: The patients with active CD who received UST treatment were retrospectively recruited from the Department of Gastroenterology, the Second Affiliated Hospital of Wenzhou Medical University between January 2022 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crohn Disease
Share to TLR5 gene
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Toll-Like Receptor 5

Share to Treatment Outcome

Source

Identifiers

PMID: 41986121
DOI: 10.3760/cma.j.cn112137-20250903-02288

Genes

UST
TLR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Association of Toll-like receptor 5 gene polymorphism with the clinical efficacy of ustekinumab in patients with Crohn's disease].PMID 41986121Read ↗

Discovery of intestinal mRNA expression profiles correlated with mucosal healing of ustekinumab patients with Crohn’s disease: bioinformatics analysis and prospective cohort validationSemantic proximity Read ↗

[Association of microRNA gene polymorphisms with risk, clinicopathological characteristics and therapeutical efficacy among Chinese patients with Crohn's disease].Semantic proximity Read ↗

[Relationships of PAI-1 gene polymorphisms with the efficacy of ustekinumab in the treatment of patients with Crohn disease].Semantic proximity Read ↗

[Relationships of interleukin-7 receptor gene polymorphisms with the risk of Crohn's disease and the efficacy of infliximab].Semantic proximity Read ↗

Comparative Effectiveness and Safety of Ustekinumab versus Anti–TNF Therapy in Crohn Disease: A Systematic ReviewSemantic proximity Read ↗

Efficacy, drug sustainability, and safety of ustekinumab treatment in Crohn’s disease patients over three yearsSemantic proximity Read ↗

Machine learning gene expression predicting model for ustekinumab response in patients with Crohn's diseaseSemantic proximity Read ↗

A Novel Nomogram for Predicting Mucosal Healing in Crohn's Disease in ChildrenSemantic proximity Read ↗

To evaluate the predictive effect of vitamin D on clinical outcomes of infliximab treated Crohn’s disease patients in western ChinaSemantic proximity Read ↗

Association of STAT4 rs7574865 polymorphism with susceptibility to inflammatory bowel disease: A systematic review and meta-analysis.Semantic proximity Read ↗

Role of vitamin D in activity and severity of inflammatory bowel disease in Egyptian patientsSemantic proximity Read ↗

High-Throughput Whole-Exome Sequencing and Large-Scale Computational Analysis to Identify the Genetic Biomarkers to Predict the Vedolizumab Response Status in Inflammatory Bowel Disease Patients from Saudi ArabiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.