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Article

Serum and CSF cytokine profile impact clinical phenotype in pediatric MOGAD.

Journal of neuroinflammation - 14 Apr 2026

Ohashi Eri, Kohyama Kuniko, Mori Takayuki, Matsuda Shinpei, Nishida Hiroya, Miyama Sahoko, Hayakawa Itaru, Abe Yuichi, Yamada Naoki, Suzuki Motomasa, Matsubara Kohei, Fukuoka Masataka, Inoue Takeshi, Kuki Ichiro, Sakuma Hiroshi

Abstract excerpt

BACKGROUND: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) has a broad spectrum of clinical phenotypes, including acute disseminated encephalomyelitis (ADEM), optic neuritis (ON), transverse myelitis (TM), and cerebral cortical encephalitis (CCE). Although these conditions exhibit diverse outcomes and require different treatment options for relapse prevention, no biomarkers have been...

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Source

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Identifiers

PMID: 41981669
DOI: 10.1186/s12974-026-03795-2
PMCID: PMC13200450

Genes

CXCL13
CXCL8
MOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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