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Mutation-driven mechanisms underlying antibiotic resistance of Helicobacter pylori in Asia: A systematic review and meta-analysis (2000-2024).

Microbial pathogenesis - 1 Jul 2026

Dutta Spriha, Ganguly Tilottama, Sharma Nyna, Dutta Arunabh, Vij Pranav, Sharma Aditi, Verma Prashant, Som Anup, Das Rajashree

Abstract excerpt

BACKGROUND: More than half of the global population is infected with Helicobacter pylori (H. pylori). Rising antibiotic resistance has weakened the effectiveness of conventional eradication therapies. We conducted a systematic review and meta-analysis of studies published between 2000 and 2024 across Asia to evaluate the relationship between antibiotic resistance and mutations. METHODS: We did a systematic review...

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Amoxicillin
Asia
Clarithromycin
DNA Gyrase
Levofloxacin

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Penicillin-Binding Proteins

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PMID: 41966313
DOI: 10.1016/j.micpath.2026.108479

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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