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Article

Impact of whole-genome amplification on the reliability of pre-transfer cattle embryo breeding value estimates.

BMC genomics - 12 Oct 2014

Shojaei Saadi Habib A, Vigneault Christian, Sargolzaei Mehdi, Gagné Dominic, Fournier Éric, de Montera Béatrice, Chesnais Jacques, Blondin Patrick, Robert Claude

Abstract excerpt

BACKGROUND: Genome-wide profiling of single-nucleotide polymorphisms is receiving increasing attention as a method of pre-implantation genetic diagnosis in humans and of commercial genotyping of pre-transfer embryos in cattle. However, the very small quantity of genomic DNA in biopsy material from early embryos poses daunting technical challenges. A reliable whole-genome amplification (WGA) procedure would...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25305778
DOI: 10.1186/1471-2164-15-889
PMCID: PMC4201692

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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