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Article

Q1020R in the spike proteins of MERS-CoV from Arabian camels confers resistance against soluble human DPP4.

Journal of virology - 19 May 2026

Chen Nianzhen, Kleine-Weber Hannah, Alkharsah Khaled, Winkler Michael, Volz Asisa, Müller Marcel A, Corman Victor M, Drosten Christian, Hoffmann Markus, Pöhlmann Stefan

Abstract excerpt

The Middle East respiratory syndrome coronavirus (MERS-CoV) is a pre-pandemic coronavirus that is transmitted from camels, the natural reservoir, to humans and can cause severe disease. MERS cases have been documented in Arabia but not Africa, although the virus is circulating in both Arabian and African camels. Further, evidence has been provided that viruses in African camels might have a reduced capacity to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41940670
DOI: 10.1128/jvi.00282-26
PMCID: PMC13185592

Genes

DPP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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