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Low levels of soluble DPP4 among Saudis may have constituted a risk factor for MERS endemicity

12 Apr 2022

Abstract excerpt

Most of the cases of Middle East respiratory syndrome coronavirus (MERS-CoV) were reported in Saudi Arabia. Dipeptidyl peptidase-4 (DPP4) was identified as the receptor for the virus. The level of soluble DPP4 (sDPP4) was found to be reduced in MERS-CoV infected patients while high levels of sDPP4 were suggested to be protective against MERS-CoV in animal models. We investigated whether the Saudi population has...

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PMID: 35413090
DOI: 10.1371/journal.pone.0266603

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