Article
Effect of Mutations in the N-Terminal Peptide of the Coat Protein on the Structure of Potato Virus X According to Small-Angle X-Ray Scattering and Molecular Dynamics.
Biochemistry. Biokhimiia - 1 Mar 2026
Ksenofontov Alexander L, Petoukhov Maxim V, Arutyunyan Alexander M, Oleynikov Ilya P, Peters Georgy S, Baratova Lyudmila A, Arkhipenko Marina V, Nikitin Nikolai A, Karpova Olga V, Shtykova Eleonora V
Abstract excerpt
Mutations in the N-terminal peptide (Ser-Thr to Ala-Gly substitution) of the coat protein (CP) of potato virus X (PVX-ST) render its genomic RNA translationally competent, unlike in the wild-type PVX virions. Consequently, RNA within the PVX-ST virions can be translated without additional triggers (such as phosphorylation or interaction with the triple gene block 1 protein), unlike the encapsidated RNA of the...
Topics
- Potexvirus
- Capsid Proteins
- Scattering, Small Angle
- Molecular Dynamics Simulation
- X-Ray Diffraction
- Mutation
- Peptides
- Virion