Article
Peptide display on Potato virus X: molecular features of the coat protein-fused peptide affecting cell-to-cell and phloem movement of chimeric virus particles.
The Journal of general virology - 1 Oct 2006
Lico Chiara, Capuano Floriana, Renzone Giovanni, Donini Marcello, Marusic Carla, Scaloni Andrea, Benvenuto Eugenio, Baschieri Selene
Abstract excerpt
The potexvirus Potato virus X (PVX) can be modified genetically to generate chimeric virus particles (CVPs) carrying heterologous peptides fused to coat protein (CP) subunits. A spontaneous PVX mutant expressing a truncated, but functional, form of the CP has been isolated. With the aim of exploiting this virus to display peptides useful for vaccine formulations, two novel viral expression vectors based on...
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