Regionally specific and highly pleiotropic loci together mediate skeletal evolution in tropical and temperate house mice.

Abstract excerpt

When organisms are exposed to new environments, they often evolve a suite of adaptive phenotypic changes. Understanding the genetic basis of these changes gives us insight into the factors that constrain and facilitate the process of adaptation. Here, we use quantitative trait locus (QTL) mapping in wild-derived house mice from temperate and tropical environments to describe the genetic architecture of adaptive...

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