Invasive lobular and ductal breast cancers: a systematic review and metanalysis in association with BRCA1/2 mutation status.

doi:10.1016/j.ejca.2026.116692

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Article

Invasive lobular and ductal breast cancers: a systematic review and metanalysis in association with BRCA1/2 mutation status.

European journal of cancer (Oxford, England : 1990) - 15 May 2026

Corso Giovanni, Andreon Chiara, La Vecchia Carlo, Bottazzoli Elisa Ileana, Abruzzese Giuliarianna, Favilla Karin, Citterio Olivia, Spoldi Elena, Di Silvestre Susanna, De Scalzi Alessandra Margherita, Polizzi Andrea, Meduri Eleonora, Trapani Dario, Nicosia Luca, Pesapane Filippo, Bossi Daniela, Brogi Edi, Shen Sherry, Mukhtar Rita, Criscitiello Carmen, Veronesi Paolo, Gandini Sara, Magnoni Francesca, Curigliano Giuseppe

Abstract excerpt

BACKGROUND: Invasive lobular breast carcinoma (ILC) differs from invasive ductal breast carcinoma (IDC) with respect to genetic alterations and risk factors. We aimed to quantify differences in the prevalence of germline BRCA1/2 mutations between these two patients' populations. MATERIALS AND METHODS: We conducted a systematic literature search to extract data on the association between BRCA1/2 mutation status...

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Identifiers

PMID: 41930855
DOI: 10.1016/j.ejca.2026.116692

Genes

BRCA1
BRCA2

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