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Stimulation by odor generated by the Maillard reaction promotes longevity through HSF-1 in Caenorhabditis elegans.

Bioscience, biotechnology, and biochemistry - 23 Jun 2026

Yokoyama Issei, Setoyama Ou, Ohata Motoko, Osada Kazumi

Abstract excerpt

Olfaction is closely associated with aging, whereas the impact of repeated olfactory stimulation on aging process remains unclear. Therefore, we attempt to examine the anti-aging effects of the odors generated by the Maillard reaction (MR) in Caenorhabditis elegans. Chemotaxis assays revealed that nematodes were attracted to MR odors, which was abolished in the odr-3 loss-of-function mutant. These results...

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PMID: 41926130
DOI: 10.1093/bbb/zbag049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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