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Article

Utility of Urinary Extracellular Vesicles for Colorectal Cancer: Comparison of DNA Quality and MRD Detection.

Cancer science - 1 Jun 2026

Kanaka Shintaro, Yamada Takeshi, Asai Fumi, Shimizu Yuta, Uehara Kay, Matsuda Akihisa, Shinji Seiichi, Yokoyama Yasuyuki, Takahashi Goro, Iwai Takuma, Takeda Kohki, Kuriyama Sho, Miyasaka Toshimitsu, Hayashi Koki, Yoshida Hiroshi

Abstract excerpt

This study evaluated the feasibility of urinary extracellular vesicles (EVs) as a liquid biopsy source for colorectal cancer (CRC) using two predefined cohorts: 97 patients for analytical validation and 63 patients for postoperative survival analysis. We compared urinary EVs, urinary cell-free tumor DNA (ctDNA), plasma EVs, and plasma ctDNA across multiple molecular dimensions, and assessed the utility of urinary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41906796
DOI: 10.1111/cas.70368

Genes

BRAF
CD63
CD81
CD9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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