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Emergence and diversity of monkeypox virus Clade IIb sub-lineages in Nigeria (1971-2023) and its role in the 2022 global outbreak.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2026

Edet Uwem Okon, Clement Meseko, Nicodemus Mkpuma Nnabuike, Ehiakhamen Odianosen, Umar Yushau, Shittu Ismail, Adeyinka Adedeji

Abstract excerpt

The exact role played by Nigeria in the global monkeypox virus (MPXV) outbreak of 2022 remains unclear, despite exported cases to Singapore, the United Kingdom (UK), the United States of America (USA), and Israel from 2018 to 2022. We sought to resolve the origin of the 2022 MPXV global outbreak. All Nigerian MPXV whole genomes deposited in the EpiPox™ database were aligned using Nextclade v3.13.3 against the...

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PMID: 41905479
DOI: 10.1016/j.meegid.2026.105931

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