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Article

Genetic Determinants of Primary Failure of Eruption: A Comprehensive Review of PTH1R Variants.

Genes - 27 Feb 2026

Niccolini Benedetta, Lauretti Giulia, Chiurazzi Pietro, Grippaudo Cristina, Tabolacci Elisabetta

Abstract excerpt

Primary Failure of Eruption (PFE) is a disorder characterized by aberrant tooth eruption, in which one or more teeth fail to follow the physiological eruptive pathway and remain partially or completely embedded within the bone or soft tissues. Although the etiopathogenesis of PFE is not yet fully elucidated, several contributing factors have been identified, including genetic alterations, hormonal disturbances,...

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Identifiers

PMID: 41898811
DOI: 10.3390/genes17030279
PMCID: PMC13025265

Genes

PTH1R

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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