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Article

Thrombophilia and Folate Cycle Gene Polymorphisms in the Development of Ischemic Stroke After COVID-19.

International journal of molecular sciences - 13 Mar 2026

Kadirovna Dildora Khaydarova, Khaydarov Nodirjon Kadirovich, Rakhmatova Sanobar Nizamovna, Salomova Nilufar Kahhorovna, Gaffarova Visola Furkatovna, Sadulloyeva Qunduz Abdullo Qizi, Sadullayev Dilshod Izbilloyevich, Berdiyev Mukhammadjon Kahramon Ugli, Djumayev Bakhodir Igamovich, Shukrulloeva Nodirabegim Akbarovna, Mukhamadieva Ferangiz Shuxratovna, Abdusattotovich Ibodov Bekzod, Khodjieva Dilbar Tadjievna

Abstract excerpt

COVID-19 not only affects the respiratory system but also increases the risk of cerebrovascular complications, including ischemic stroke. Experimental and clinical data suggest that cytokine dysregulation and polymorphisms of thrombophilia-related genes (MTHFR, MTR, and MTRR) may jointly promote hypercoagulation, endothelial dysfunction, and thromboinflammation, thereby contributing to post-COVID ischemic stroke....

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Source

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Identifiers

PMID: 41898515
DOI: 10.3390/ijms27062650
PMCID: PMC13026903

Genes

MTHFR
MTR
MTRR
TNF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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