Genetic variations associated with immediate hypersensitivity reactions to iodinated contrast media: A whole exome sequencing study.

Abstract excerpt

OBJECTIVE: The use of iodinated contrast media (ICM) in computed tomography (CT) has increased significantly; however, hypersensitivity reactions (HSRs) remain a concern. This study aimed to investigate genetic factors associated with ICM-induced immediate HSRs using whole exome sequencing (WES). MATERIALS AND METHODS: We conducted a case-control study including 20 patients with ICM-induced immediate HSRs and 11...

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