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Article

Identification and pedigree analysis of a hidden partial D antigen with rare RHD*DV.1 allele.

Laboratory medicine - 9 Feb 2026

Yuan Xiaohua, Shao Xuefeng, Xu Chunzi, Wang Jing, Sun Xiaoye, Wang Kecheng

Abstract excerpt

INTRODUCTION: An 85-year-old O D-positive male with a history of multiple D-positive RBC transfusions (10.5 units in 2020, 5.5 units in 2023) presented with severe anemia in June 2024. Unexpected antibodies were found in his plasma, and crossmatching was incompatible with all O D-positive donor RBCs. In this article, we document the methodology for confirming a hidden partial D antigen with rare RHD*DV.1 allele...

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Identifiers

PMID: 41883022
DOI: 10.1093/labmed/lmag005

Genes

RHD

Variants

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