Article
HTLV-1 genetic diversity of 52 complete sequences from 14 African countries reveals novel variants and a lack of typical P12/P8 and P30 accessory proteins in HTLV-1b, d, and f genotypes.
Emerging microbes & infections - 1 Dec 2026
Cassar Olivier, Djuicy Délia Doreen, Begliomini Giovanni, Ramassamy Jill-Léa, Oloumbou Eldridge Fredricksen, Mouinga-Ondeme Augustin, Njouom Richard, Marcais Ambroise, Deruelle Emilie, Hermine Olivier, Soriano Vincente, de Mendoza Carmen, Taylor Graham, Afonso Philippe V, Gessain Antoine
Abstract excerpt
Central Africa is the largest region of human T-cell Leukaemia virus (HTLV-1) endemicity with several million people estimated to be infected. Based on the study of the LTR region, it is also the region with the highest HTLV-1 diversity, with the presence of genotypes a-b and d-g. However, complete genomic sequences are still lacking for Central African genotypes. Here, we report the first large collection of...
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