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Article

Genetic predisposition to coffee consumption and the association with the early risk of atherosclerosis.

Scientific reports - 22 Mar 2026

Qiao Xiangyu, Toma Vanessa William, Wang Jing, Herraiz-Adillo Ángel, Söderholm Simon, Berglind Daniel, Calling Susanna, Daka Bledar, Martinell Mats, Bergman Frida, Henriksson Pontus, Ghafouri Bijar, Ulander Martin, Östgren Carl Johan, Cantù Claudio, Zhong Wen, Iredahl Fredrik

Abstract excerpt

The cardiovascular effects of coffee consumption remain debated, particularly regarding early-stage subclinical atherosclerosis. This study investigated the association between coffee intake, genetic predisposition, and the risk of subclinical coronary and carotid atherosclerosis in 24,835 participants from the Swedish CArdioPulmonary bioImage Study (SCAPIS). Coffee intake was assessed via self-reported...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41865070
DOI: 10.1038/s41598-026-44122-2
PMCID: PMC13009213

Genes

AHR
CCL17
CYP1A1
CYP1A2
DLK1
IL1RL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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