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Article

Secondary Aplastic Anemia During Osimertinib Treatment for Lung Adenocarcinoma: A Case Report.

The Tokai journal of experimental and clinical medicine - 20 Apr 2026

Takihara Takahisa, Hara Ryujiro, Tsuchiya Nanami, Takahashi Mari, Enokida Keito, Sadahiro Kozaburo, Yamada Masatoshi, Asano Koichiro

Abstract excerpt

We report a case of a 79-year-old woman with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer who developed secondary aplastic anemia during treatment with the EGFR tyrosine kinase inhibitor (TKI) osimertinib. In the 23rd week of osimertinib treatment, the patient developed pancytopenia accompanied by fatty bone marrow. Discontinuation of osimertinib and initiation of treatment with...

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PMID: 41859810

Genes

EGFR

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