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Osimertinib-Associated Toxic Epidermal Necrolysis in a Lung Cancer Patient Harboring an EGFR Mutation-A Case Report and a Review of the Literature.

Medicina (Kaunas, Lithuania) - 11 Aug 2020

Sato Izumi, Mizuno Hiroki, Kataoka Nobutaka, Kunimatsu Yusuke, Tachibana Yusuke, Sugimoto Takumi, Tani Nozomi, Ogura Yuri, Hirose Kazuki, Takeda Takayuki

Abstract excerpt

Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are life-threatening dermatologic adverse events in the same category, caused by a delayed-type drug hypersensitivity reaction. Although skin toxicity is common during treatment with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), osimertinib-associated TEN is quite rare-thus far, only one report has been published from...

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Identifiers

PMID: 32796633
DOI: 10.3390/medicina56080403
PMCID: PMC7466304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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