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Pancreatectomy Outcomes in Pediatric Hyperinsulinism: A Retrospective Single-Center Experience.

The Journal of surgical research - 1 Apr 2026

Ozaydin Seyithan, Coskun Nihal, Yildiz Ozaydin Ipek, Cologlu Ozlem

Abstract excerpt

INTRODUCTION: Hyperinsulinism (HI) is the most frequent cause of persistent hypoglycemia in neonates and infants. Untreated, this condition can cause permanent neurological impairment. Medical therapies such as diazoxide and octreotide are effective in some cases, but patients with severe KATP-adenosine triphosphate sensitive potassium channel mutations are often unresponsive, requiring surgery. This study...

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Congenital Hyperinsulinism
Hyperinsulinism
Infant
Infant, Newborn
Pancreatectomy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Potassium Channels, Inwardly Rectifying

Sulfonylurea Receptors

Treatment Outcome

Source

Identifiers

PMID: 41832879
DOI: 10.1016/j.jss.2026.02.002

Genes

ABCC8
KCNJ11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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