Investigating the Impact of Host Genetics on the Risk of Disease Progression in Individuals With Influenza.

doi:10.1002/iid3.70394

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Investigating the Impact of Host Genetics on the Risk of Disease Progression in Individuals With Influenza.

Immunity, inflammation and disease - 1 Mar 2026

Mørup Sara Bohnstedt, Milojevic Maja, Shahri Seyed Mahmood Taghavi, Sherman Brad T, Chang Weizhong, Lynfield Ruth, Helleberg Marie, Skeans Melissa, Østergaard Lars, Borgwardt Line, Gerry Norman, Losso Marcelo, Baillie Kenneth, Davey Richard, Dwyer Dominic E, Phetsouphanh Chansavath, Papastamopoulos Vasileios, Novak Richard M, Murray Daniel D, Reekie Joanne, Lundgren Jens D, Lane H Clifford, Reilly Cavan

Abstract excerpt

BACKGROUND: Knowledge of the human genetic contribution to the risk of complications from influenza is limited. This study assessed the association between human single-nucleotide polymorphisms (SNPs) and disease progression in individuals with influenza. METHODS: A targeted analysis of 10 SNPs with prior evidence in COVID-19 and a genome-wide association study (GWAS) were used to assess associations between SNPs...

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Identifiers

PMID: 41814526
DOI: 10.1002/iid3.70394
PMCID: PMC13098070

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