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Article

Vitamin D supplementation during pregnancy and offspring bone microarchitecture: A post hoc analysis of the MAVIDOS randomised controlled trial.

Bone - 1 Jun 2026

Maden Charlotte, D'Angelo Stefania, Westbury Leo D, Curtis Elizabeth M, Crozier Sarah R, Godfrey Keith M, Ward Kate A, Cooper Cyrus, Harvey Nicholas C, Moon Rebecca J

Abstract excerpt

BACKGROUND: Randomised trials have shown that pregnancy vitamin D supplementation results in greater offspring bone mineral density (BMD) in childhood. The effect of this intervention on bone microarchitecture, a further determinant of bone strength, and possible interactions with genetic variation in vitamin D metabolism, have not previously been investigated. We investigated these in a post hoc analysis of a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41802552
DOI: 10.1016/j.bone.2026.117843

Genes

CYP24A1
CYP2R1
DHCR7
GC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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