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Metabolomic Profiling of Fecal Samples Reveals Distinct Signatures Associated with Disease Phenotypes and Locations in Crohn's Disease.

Digestive diseases and sciences - 1 Aug 2026

Tan Tingyi, Vincent Matthew, Jain Umang, Deepak Parakkal

Abstract excerpt

BACKGROUND: Crohn's disease is a heterogeneous, transmural inflammatory condition that can involve any segment of the gastrointestinal tract. Distinct locations (ileal, colonic, ileocolonic) and phenotypes (inflammatory, stricturing, penetrating) display different clinical behaviors and complication risks in CD. Whether these location- and phenotype-specific patterns correspond to unique metabolomic profiles...

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Chromatography, High Pressure Liquid
Crohn Disease
Feces
Ileum
Leukocyte L1 Antigen Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tandem Mass Spectrometry

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PMID: 41801634
DOI: 10.1007/s10620-026-09779-9
PMCID: PMC13274631

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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