Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative sensory testing-based sensory phenotypes align with measures of peripheral nerve damage in patients with painful polyneuropathies.

Pain - 1 Jun 2026

Galosi Eleonora, Leone Caterina, Falco Pietro, Di Pietro Giuseppe, De Stefano Gianfranco, Esposito Nicoletta, Evangelisti Enrico, Litewczuk Daniel, Tramontana Lorenzo, Costanzo Rocco, Di Stefano Giulia, Truini Andrea

Abstract excerpt

ABSTRACT: Quantitative sensory testing (QST) is increasingly used to stratify patients with peripheral neuropathic pain into sensory phenotypes that may reflect distinct underlying pain mechanisms. Yet, their correspondence with objective measures of peripheral nerve damage remains unclear. This study investigated whether QST-based phenotypes are associated with objective measures of peripheral nerve damage in...

Topics

Join the communities discussing this publication.

Action Potentials
Hyperalgesia
Neural Conduction
Neuralgia
Pain Measurement

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polyneuropathies

TRPV Cation Channels

Ubiquitin Thiolesterase

Source

Identifiers

PMID: 41800740
DOI: 10.1097/j.pain.0000000000003948

Genes

GAP43
TRPV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative sensory testing-based sensory phenotypes align with measures of peripheral nerve damage in patients with painful polyneuropathies.PMID 41800740Read ↗

Sensory Phenotypes Provide Insight Into the Natural Course of Diabetic Polyneuropathy.Semantic proximity Read ↗

Symptom profiles in the painDETECT Questionnaire in patients with peripheral neuropathic pain stratified according to sensory loss in quantitative sensory testing.Semantic proximity Read ↗

Sensory phenotype and risk factors for painful diabetic neuropathy: a cross-sectional observational study.Semantic proximity Read ↗

A standardized clinical evaluation of phenotypic diversity in diabetic polyneuropathy.Semantic proximity Read ↗

Responsiveness of quantitative sensory testing-derived sensory phenotype to disease-modifying intervention in patients with entrapment neuropathy: a longitudinal study.Semantic proximity Read ↗

Sensory testing might not be perfect - but it is the best biomarker for pain phenotypes we have right now.Semantic proximity Read ↗

Peripheral Neuropathy: A Phenotype-Driven Review for Diagnosis and Management.Semantic proximity Read ↗

Impact of different CRPS phenotypes and diagnostic criteria on quantitative sensory testing outcomes: systematic review and meta-analysis.Semantic proximity Read ↗

A diminished sciatic nerve structural integrity is associated with distinct peripheral sensory phenotypes in individuals with type 2 diabetes.Semantic proximity Read ↗

Small‐fibre damage is associated with distinct sensory phenotypes in patients with fibromyalgia and small‐fibre neuropathySemantic proximity Read ↗

Association of sensory phenotype with quality of life, functionality, and emotional well-being in patients suffering from neuropathic pain.Semantic proximity Read ↗

Pathophysiological mechanisms of neuropathic pain: comparison of sensory phenotypes in patients and human surrogate pain models.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.