Article
Pathophysiological mechanisms of neuropathic pain: comparison of sensory phenotypes in patients and human surrogate pain models.
Pain - 1 Jun 2018
Vollert Jan, Magerl Walter, Baron Ralf, Binder Andreas, Enax-Krumova Elena K, Geisslinger Gerd, Gierthmühlen Janne, Henrich Florian, Hüllemann Philipp, Klein Thomas, Lötsch Jörn, Maier Christoph, Oertel Bruno, Schuh-Hofer Sigrid, Tölle Thomas R, Treede Rolf-Detlef
Abstract excerpt
As an indirect approach to relate previously identified sensory phenotypes of patients suffering from peripheral neuropathic pain to underlying mechanisms, we used a published sorting algorithm to estimate the prevalence of denervation, peripheral and central sensitization in 657 healthy subjects undergoing experimental models of nerve block (NB) (compression block and topical lidocaine), primary hyperalgesia...
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