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A diminished sciatic nerve structural integrity is associated with distinct peripheral sensory phenotypes in individuals with type 2 diabetes.

Diabetologia - 1 Feb 2024

Mooshage Christoph M, Tsilingiris Dimitrios, Schimpfle Lukas, Seebauer Lukas, Eldesouky Omar, Aziz-Safaie Taraneh, Hohmann Anja, Herzig Stephan, Szendroedi Julia, Nawroth Peter, Heiland Sabine, Bendszus Martin, Kurz Felix T, Kopf Stefan, Jende Johann M E, Kender Zoltan

Abstract excerpt

AIMS/HYPOTHESIS: Quantitative sensory testing (QST) allows the identification of individuals with rapid progression of diabetic sensorimotor polyneuropathy (DSPN) based on certain sensory phenotypes. Hence, the aim of this study was to investigate the relationship of these phenotypes with the structural integrity of the sciatic nerve among individuals with type 2 diabetes. METHODS: Seventy-six individuals with...

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Advanced Neuroimaging Techniques and Applications
Cross-Sectional Studies
Diabetes Mellitus, Type 2
Diabetic Neuropathies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Diffusion Tensor Imaging

Pain Mechanisms and Treatments

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PMID: 38019287
DOI: 10.1007/s00125-023-06050-y
PMCID: PMC10789832

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