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Genomic characterization of a novel human astrovirus MLB1 variant from Tanzania.

Virology - 1 Jun 2026

Shayo Mariana J, Kuchaka Davis, Beti Melkiory, Mwing'a Gerald Phares, Kimu Patrick, Wadugu Boaz, Juma Masoud A, Kumburu Happiness, Kiwelu Ireen, Ali Mohamed, Kazyoba Paul, Clausen Philip L C, Muro Florida, Mmbaga Blandina T, Alifrangis Michael, Aarestrup Frank M, Sonda Tolbert

Abstract excerpt

Human astroviruses (HAstV) are emerging viral pathogens responsible for gastroenteritis worldwide, but whole-genome data from Africa, including from Tanzania, remains scarce. A genomic analysis of stools of children with diarrhea was performed using nanopore sequencing. We successfully assembled HAstV-MLB1 complete genomes from two different stool samples, achieving high sequence coverage of 354.75x and 769.94x,...

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PMID: 41795259
DOI: 10.1016/j.virol.2026.110861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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