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Article

Neuroimaging subtypes of adolescent sleep insufficiency stratify natural short sleepers from comorbidity or environment driven insufficiency.

Nature communications - 7 Mar 2026

Chen Yiwei, Li Mingyang, Zhao Zhiyong, Xu Xinyi, Huang Yongquan, Chen Ruike, Zhao Ruoke, Wang Guanghai, Jiang Fan, Wu Dan

Abstract excerpt

Insufficient sleep (less than 8 hours for adolescents) has heterogeneous neurobiological underpinnings. Using the SuStaIn model on brain MRI from ABCD Study, we identified three distinct subtypes with reduced cortical thickness, starting from the postcentral, pericalcarine, and entorhinal cortices. The subtypes diverged in sleep-related determinants. The postcentral subtype mirrored the controls of sufficient...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41794771
DOI: 10.1038/s41467-026-70135-6
PMCID: PMC13096203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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