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Article

Predicting identity dissociation using childhood maltreatment and genetic variation in the stress-response gene FKBP5: a machine learning analysis.

Scientific reports - 6 Mar 2026

Kratzer Leonhard, Knoblauch Hans, Powers Abigail, Katrinli Seyma, Michopoulos Vasiliki, Fani Negar, Gillespie Charles F, Jovanovic Tanja, Ressler Kerry J, Smith Alicia K, Müller-Myhsok Bertram, Tschöke Stefan

Abstract excerpt

Identity dissociation is challenging to detect and treat, and its etiology remains incompletely understood. Childhood maltreatment and FKBP5 polymorphisms, which modulate the stress response, may contribute by disrupting the integration of autobiographical experiences essential for identity development. We examined whether gene-environment interactions involving childhood maltreatment and FKBP5 polymorphisms...

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Identifiers

PMID: 41792431
DOI: 10.1038/s41598-026-42512-0
PMCID: PMC12972126

Genes

FKBP5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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