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Article

A radio-genomics biomarker for precision epidermal growth factor receptor mutation targeting therapy in non-small cell lung cancer.

Scientific reports - 6 Mar 2026

Chen Mitchell, Copley Susan J, Linton-Reid Kristofer, Viola Patrizia, Han Yidong, Cortellini Alessio, Lu Haonan, Mani Aleksander, Bahket Marize, Pinato David J, Power Danielle, Rockall Andrea G, Aboagye Eric O

Abstract excerpt

Newer-generation tyrosine kinase inhibitors (TKIs) have shown increasing efficacy in cancers driven by specific mutations, with epidermal growth factor receptor (EGFR) alterations remaining the most common actionable targets in non-small cell lung cancer (NSCLC). Treatment decisions are currently guided by tissue sampling and genetic testing, which are limited by procedural risks, patient tolerance, tumour...

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Identifiers

PMID: 41792401
DOI: 10.1038/s41598-026-42948-4
PMCID: PMC13083983

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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