Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Simple virilizing form of 21-hydroxylase deficiency presenting with renal Insufficiency and polycythemia: a case report.

Frontiers in endocrinology - 1 Jan 2026

Liang Lu, Su Xudong, Zhang Yifan, Wang Zheng, Zhang Guifeng, Bai Jie, Li Jian

Abstract excerpt

The simple virilizing (SV) form of 21-hydroxylase deficiency (21-OHD) is primarily characterized by androgen excess. Gonadal dysfunction is widely acknowledged; however, systemic complications, including renal injury, are often overlooked. This report presents a rare case involving a 25-year-old female diagnosed with SV 21-OHD, who subsequently experienced unanticipated renal insufficiency and secondary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Hyperplasia, Congenital
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polycythemia

Share to Renal Insufficiency

Share to Steroid 21-Hydroxylase

Share to Virilism

Source

Open in PubMed Open full text

Identifiers

PMID: 41788783
DOI: 10.3389/fendo.2026.1759387
PMCID: PMC12956689

Genes

CYP21A2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Simple virilizing form of 21-hydroxylase deficiency presenting with renal Insufficiency and polycythemia: a case report.PMID 41788783Read ↗

Two brothers with non-classical 21-hydroxylase deficiency: to treat or not to treat?Semantic proximity Read ↗

Severe Hyperandrogenism in 46,XX Congenital Adrenal Hyperplasia: Molecular Physiopathology, Late Diagnoses, and Personalized Management.Semantic proximity Read ↗

Simple virilising congenital adrenal hyperplasia in monozygotic twins: A rare report and review of previous cases.Semantic proximity Read ↗

[Steroid 21-hydroxylase deficiencies and female infertility: pathophysiology and management].Semantic proximity Read ↗

Recent advances in the diagnosis and management of congenital adrenal hyperplasia due to 21-hydroxylase deficiency.Semantic proximity Read ↗

Congenital Adrenal Hyperplasia with Combined 21-hydroxylase deficiency and 17α-hydroxylase/17,20-lyase deficiency: An undervirilized male.Semantic proximity Read ↗

Steroid 21-hydroxylase deficiency (congenital adrenal hyperplasia).Semantic proximity Read ↗

[Clinical report of testicular hypoplasia combined with 21-hydroxylase deficiency].Semantic proximity Read ↗

Clinical and Biochemical Phenotype Across the Genotypic Spectrum of 21-hydroxylase Deficiency in 457 Individuals.Semantic proximity Read ↗

Case report: Development of central precocious puberty in a girl with late-diagnosed simple virilizing congenital adrenal hyperplasia complicated with Williams syndrome.Semantic proximity Read ↗

Prenatal diagnosis and treatment of congenital adrenal hyperplasia owing to 21-hydroxylase deficiency.Semantic proximity Read ↗

21-Hydroxylase deficiency presenting as massive bilateral adrenal masses in the seventh decade of life.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.