Article
[Clinical report of testicular hypoplasia combined with 21-hydroxylase deficiency].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Feb 2018
Jiang Bo, Ma Dingyuan, Chen Huanhuan, Yang Xiaoyu, Cui Yugui, Xu Zhengfeng, Liu Jiayin
Abstract excerpt
OBJECTIVE To investigate the correlation of 21-hydroxylase deficiency (21-OHD) with male testicular dysplasia. METHODS Clinical data of 8 infertile males with congenital adrenal hyperplasia due to 21-OHD was retrospectively analyzed. In addition, potential mutations of the CYP21A2 gene was detected. RESULTS All patients were referred because of azoospermia or severe oligospermia and had small testis with averaged...
Topics
- Adrenal Hyperplasia, Congenital
- Adult
- Azoospermia
- Base Sequence
- DNA Mutational Analysis
- Humans
- Infertility, Male
- Male
- Mutation
- Oligospermia
- Retrospective Studies
- Steroid 21-Hydroxylase
- Testicular Diseases
- Testis