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Article

Role of MEG3-miRNAs in immune-inflammatory regulation in age-dependent wool follicle remodeling in Tan sheep.

BMC genomics - 27 Feb 2026

Zhang Letian, Yao Jiajie, Zhao Zhengwei, Ma Lina, Ma Qing, Wang Jiankui, Deng Xuemei

Abstract excerpt

BACKGROUND: The “nine-curve” crimped wool is a key economic trait of Tan sheep, which peaks at 35 days of age and disappears in adulthood. However, the regulatory mechanisms underlying this age-dependent trait remain unclear. This study aimed to decipher these mechanisms by analyzing the skin of Tan sheep across critical developmental stages. RESULTS: We integrated small RNA sequencing, mRNA sequencing, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41761054
DOI: 10.1186/s12864-026-12688-w
PMCID: PMC13049868

Genes

ARL1
HOXC6
KRT5
KRT71
MX1
RAB10
RILPL2
ST7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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