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A Developmental Gene Expression Atlas Reveals Novel Biological Basis of Complex Phenotypes in Sheep.

Genomics, proteomics & bioinformatics - 10 May 2025

Zhao Bingru, Luo Hanpeng, Fu Xuefeng, Zhang Guoming, Clark Emily L, Wang Feng, Dalrymple Brian Paul, Oddy V Hutton, Vercoe Philip E, Wu Cuiling, Liu George E, Li Cong-Jun, Xiang Ruidong, Tian Kechuan, Zhang Yanli, Fang Lingzhao

Abstract excerpt

Sheep (Ovis aries) represent one of the most important livestock species for global animal protein and wool production. However, little is known about the genetic and biological basis of ovine phenotypes, particularly those with high economic value and environmental impact. Here, by integrating 1413 RNA sequencing (RNA-seq) samples from 51 distinct tissues across 14 developmental time points, representing...

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PMID: 40037845
DOI: 10.1093/gpbjnl/qzaf020
PMCID: PMC12228968

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GNRHR
PRKDC
SOX9

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