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Narrow Versus Broad Phenotype Definitions Affect Genetic Analysis of Language More than Other Broad Autism Phenotype Traits.

Genes - 25 Jan 2026

Lodi Mudassir K, Flax Judy F, Gwin Christine, Wilson Sherri, Robinson Amber, Buyske Steven, Brzustowicz Linda M, Xing Jinchuan, Bartlett Christopher W

Abstract excerpt

BACKGROUND/OBJECTIVES: Autism spectrum disorder (ASD) is a heritable neurodevelopmental condition that displays heterogeneity in both presentation and etiology, and often presents with concomitant communication difficulties. The hypothesis behind the New Jersey Language and Autism Genetic Study is that genetic heterogeneity for component phenotypes of ASD may be reduced relative to the disorder as a whole. We...

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Source

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Identifiers

PMID: 41751509
DOI: 10.3390/genes17020125
PMCID: PMC12940878

Genes

DNAH3
ZNF774

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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