Association between the CYP24A1 rs2762939 polymorphism and vascular calcification in Indonesian patients with chronic kidney disease on hemodialysis.

doi:10.52225/narra.v5i3.2874

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Article

Association between the CYP24A1 rs2762939 polymorphism and vascular calcification in Indonesian patients with chronic kidney disease on hemodialysis.

Narra J - 1 Dec 2025

Wendy Wendy, Muzasti Riri A, Tarigan Radar R

Abstract excerpt

Vitamin D plays a key role in mineral metabolism, and its dysregulation contributes to vascular calcification, a major complication of chronic kidney disease-mineral and bone disorder (CKD-MBD) in patients undergoing hemodialysis with CKD. The CYP24A1 gene encodes 24-hydroxylase, the enzyme responsible for degrading active vitamin D metabolites and its polymorphisms, particularly rs2762939, have been linked to...

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Identifiers

PMID: 41743882
DOI: 10.52225/narra.v5i3.2874
PMCID: PMC12931500

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CYP24A1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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