Coexistence of a primary ALK-positive and MET14 exon skipping mutation double-fusion in one patient with NSCLC and response to crizotinib: A case report and literature review.

Abstract excerpt

RATIONALE: Lung cancer exhibits one of the highest incidence and fatality rates globally. With the advancement of next-generation sequencing testing techniques, double or multiple gene driver mutations have been identified in certain patients. PATIENT CONCERNS: A 78-year-old female presented with a chest shadow. DIAGNOSES: In this case of lung adenocarcinoma, second-generation sequencing revealed a co-occurrence...

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