Altered phenotype and gene expression of regulatory T cells (Tregs) in children with Autism, and the relationship with comorbid gastrointestinal symptoms.

Abstract excerpt

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by social deficits and stereotypic behaviors. In ASD, increased numbers of inflammatory cells and their mediators have been found in peripheral blood, brain, and gastrointestinal (GI) tissues. Regulatory T cells (Tregs) play a crucial role in suppressing inflammatory processes that, if disrupted, can result in inflammation and...

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