Article
Genomic approaches to accelerate American chestnut restoration.
Science (New York, N.Y.) - 12 Feb 2026
Westbrook Jared W, Malukiewicz Joanna, Zhang Qian, Sreedasyam Avinash, Jenkins Jerry W, Lakoba Vasiliy, Fitzsimmons Sara, Van Clief Jamie, Collins Kendra, Hoy Stephen, Stark Cassie, Graboski Lake, Jenkins Eric, Saielli Thomas M, Jarrett Benjamin T, Wigfield Lucinda J, Kerwien Lauren M, Wilbur Ciera, Sandercock Alexander M, Craddock J Hill, Keriö Susanna, Zhebentyayeva Tetyana, Fan Shenghua, Thomas Austin M, Abbott Albert G, Nelson C Dana, Xia Xiaoxia, McKenna James R, Kell Caleb, Williams Melissa, Boston LoriBeth, Plott Christopher, Carle Florian, Swatt Jack, Ostroff Jack, Jeffers Steven N, McKeever Kathleen, Smith Erica, Ellis Thomas J, James Joseph B, Sisco Paul, Newhouse Andrew, Carlson Erik, Powell William A, Hebard Frederick V, Scrivani John, Heverly Caragh, Cipollini Martin, Clark Brian, Evans Eric, Levine Bruce, Carlson John E, Goodstein David, Orebaugh Jack, Yang Zamin K, Martin Madhavi Z, Tannous Joanna, Rush Tomás A, Engle Nancy L, Tschaplinski Timothy J, Grimwood Jane, Schmutz Jeremy, Holliday Jason A, Lovell John T
Abstract excerpt
More than a century after two introduced pathogens killed billions of American chestnut trees, introgression of resistance alleles from Chinese chestnuts has contributed to the recovery of self-sustaining populations. However, progress has been slow because of the complex genetic architecture of resistance. To better understand blight resistance, we compared reference genomes, gene expression responses, and stem...
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