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Article

Assessment of a High-Resolution HPLC System to Quantify HbE for α0-Thalassemia Diagnosis in HbE Heterozygotes.

Annals of laboratory medicine - 1 Sept 2026

Srisuwan Wibhasiri, Satthakarn Surada, Panyasai Sitthichai

Abstract excerpt

Background: HbE and α0-thalassemia are highly prevalent in Southeast Asia and co-inherited in asymptomatic carriers. α0-Thalassemia screening in HbE heterozygotes relies on HbE quantification. We evaluated the performance of a high-resolution HPLC system in quantifying HbE and HbA2 to distinguish HbE heterozygotes with and without α0-thalassemia. Methods: HbE heterozygotes (N=650) presenting EA patterns on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41672632
DOI: 10.3343/alm.2025.0552
PMCID: PMC13458170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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