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Article

Integrative GWAS and RNA-seq identify MYL9 as a key regulator of pullorum disease resistance in chickens.

Poultry science - 1 Apr 2026

Wu Jiongwen, Fan Zhexia, Chao Xiaohuan, Liang Weiming, Li Ruina, Chen Shuya, Fang Cheng, Luo Qingbin

Abstract excerpt

Pullorum disease, caused by Salmonella Pullorum, is a significant avian disease that poses a serious threat to poultry health. To elucidate the host immune response characteristics and key regulatory gene mechanisms during infection, this study investigated 2,100 White Plymouth Rock hens at 100 days of age. A rapid plate agglutination (RPA) test was conducted for screening, identifying 175 individuals as strongly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41671841
DOI: 10.1016/j.psj.2026.106544
PMCID: PMC12914420

Genes

MYL9
TNF
KCNH4
KLHL38
SYT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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