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Increased Gut Microbiota Diversity in Patients With Retinitis Pigmentosa and Implications for Disease Phenotypes and Progression.

Investigative ophthalmology & visual science - 2 Feb 2026

Hasegawa Tomoko, Iwai Sachiko, Ikeda Hanako Ohashi, Miyaoka Daichi, Sato Noriaki, Fujimoto Kosuke, Wei Xinyi, Kusaka Mami, Miyata Manabu, Numa Shogo, Otsuka Yuki, Imoto Seiya, Uematsu Satoshi, Tsujikawa Akitaka

Abstract excerpt

Purpose: Inflammation is often present in retinitis pigmentosa (RP) and is reported to affect visual outcome. Gut microbiota plays a crucial role in inflammatory diseases. This study aimed to elucidate the relationship between the gut microbiota and RP. Methods: The 16S rRNA gene sequencing analysis was performed on stool samples collected from 103 patients with RP and 64 healthy individuals. The α and β...

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Identifiers

PMID: 41670415
DOI: 10.1167/iovs.67.2.27
PMCID: PMC12908715

Genes

NLRP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

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