Article
RamEx: an R package for high-throughput microbial ramanome analyses with accurate quality assessment.
Microbiome - 10 Feb 2026
Zhang Yanmei, Jing Gongchao, Chen Rongze, Gong Yanhai, Li Yuandong, Wang Yongshun, Wang Xixian, Zhang Jia, Mao Yuli, He Yuehui, Zheng Xiaoshan, Wang Mingchao, Yuan Hao, Xu Jian, Sun Luyang
Abstract excerpt
BACKGROUND: Microbial single-cell Raman spectroscopy (SCRS) has emerged as a powerful tool for label-free phenotyping, enabling rapid characterization of microbial diversity, metabolic states, and functional interactions within complex communities. However, high-throughput SCRS datasets often contain spectral anomalies from noise and fluorescence interference, which obscure microbial signatures and hinder...
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