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Article

Urinary Microbiome and Metabolome Differentiate Overactive Bladder From the Physiological State, and Reflect Recent Antibiotic Use and Treatment Response.

The Journal of urology - 1 Jul 2026

Werneburg Glenn T, Gross Michael D, Hettel Daniel R, Lyon Madison, Jeong Stacy H, McSweeney Sean, Knorr Jacob M, Adler Ava, Dang Thien, Orji Peace, Ramanujan Suruchi, Goldman Howard B, Vasavada Sandip P, Miller Aaron W

Abstract excerpt

PURPOSE: To characterize and compare the bacterial urinary microbiome in individuals with and without overactive bladder (OAB), and secondarily compare its composition by phenotype, comorbidities, recent antibiotic exposure, and therapeutic response. MATERIALS AND METHODS: We isolated DNA and metabolites from the urine of women without urologic diagnoses and with OAB. Bacterial profiles were generated with 16S...

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PMID: 41666295
DOI: 10.1097/JU.0000000000004990

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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